{"id":756,"date":"2014-08-20T15:10:19","date_gmt":"2014-08-20T15:10:19","guid":{"rendered":"http:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/?p=756"},"modified":"2014-08-20T15:10:19","modified_gmt":"2014-08-20T15:10:19","slug":"seminario-expresion-de-proteinas-en-sistemas-de-celulas-de-mamiferos-2","status":"publish","type":"post","link":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/2014\/08\/20\/seminario-expresion-de-proteinas-en-sistemas-de-celulas-de-mamiferos-2\/","title":{"rendered":"Seminario: Expresi\u00f3n de Prote\u00ednas en Sistemas de C\u00e9lulas de Mam\u00edferos"},"content":{"rendered":"

Fecha:<\/strong> Jueves 21 de agosto de 2014<\/p>\n

Hora: <\/strong>5:00 p.m.<\/p>\n

Lugar:<\/strong> Auditorio DeLima S.A.<\/p>\n

T\u00edtulo del Seminario: <\/strong>Expresi\u00f3n de prote\u00ednas en sistemas de c\u00e9lulas de mam\u00edferos<\/p>\n

A cargo de:<\/strong> Natasha Skoko, Ph.D. en Biolog\u00eda Molecular de la Universidad Belgrado, Serbia. Actualmente trabaja como responsable de la producci\u00f3n de prote\u00ednas terap\u00e9uticas en c\u00e9lulas de mam\u00edfero en el grupo de desarrollo Biotecnol\u00f3gico del ICGEB en Trieste, Italia<\/p>\n

Resumen:<\/strong><\/p>\n

Los sistemas de expresi\u00f3n en c\u00e9lulas de mam\u00edfero, se ha convertido en el m\u00e9todo de producci\u00f3n de prote\u00ednas recombinantes dominante en las aplicaciones cl\u00ednicas debido a que las c\u00e9lulas de mam\u00edferos poseen la capacidad de realizar modificaci\u00f3n postraduccional semejante a las prote\u00ednas hechas en humanos. El 70% de los medicamentos biol\u00f3gicos hechos en c\u00e9lulas de mam\u00edfero usan como sistema de expresi\u00f3n c\u00e9lulas de ovario de h\u00e1mster (CHO) debido a que poseen una maquinaria muy eficiente para realizar patrones de glicosilaciones id\u00e9nticas a las de humanos. En este seminario se discutir\u00e1 los \u00faltimos avances logrados en este sistema de expresi\u00f3n y cuales son los sistemas de producci\u00f3n de prote\u00ednas recombinantes mas utilizados actualmente.<\/p>\n

\"Natasha<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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T\u00edtulo del Seminario: Expresi\u00f3n de prote\u00ednas […]","_links":{"self":[{"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/posts\/756"}],"collection":[{"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/users\/1219"}],"replies":[{"embeddable":true,"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/comments?post=756"}],"version-history":[{"count":1,"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/posts\/756\/revisions"}],"predecessor-version":[{"id":758,"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/posts\/756\/revisions\/758"}],"wp:attachment":[{"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/media?parent=756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/categories?post=756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.icesi.edu.co\/blogs\/facultad_ciencias_naturales\/wp-json\/wp\/v2\/tags?post=756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}